Kumar, A.
Dr. Ashutosh Kumar
Professor
Phone: +(91-22) 2576 7762
E-mail: ashutoshk [at] iitb.ac.in
Location: Room No. 606, BSBE Building
Lab web page
Research Interest
- Structural Biology, Biophysics,Solid and Liquid-state NMR Spectroscopy, Protein-Protein, Protein-lipid and Protein-drug interactions.
Academic Background
- B. Sc. (Chemistry (Hons.) with Physics and Mathematics) from Faculty of Science, Banaras Hindu University, Varanasi, India (1996 – 1999)
- M. Sc. : (Chemistry) from Indian Institute of Technology (IIT) Delhi, New Delhi, India (1999 – 2001)
- Ph.D. : (Chemistry) from Department of Chemical Sciences,Tata Institute of Fundamental Research (TIFR), Mumbai, India (2001 – 2007)
Teaching (current)
Biophysical Chemistry, Drug Discovery and Development, Metabolism and Bioenergetics, Biologics and Biosimilars
Professional Experience
- Professor (2021-): Department of Biosciences and Bioengineering, IIT Bombay
- Associate Professor (2016-2021): Department of Biosciences and Bioengineering, IIT Bombay
- Assistant Professor (2011-2016): Department of Biosciences and Bioengineering, IIT Bombay
- Post-doctoral Research (2007-2010): Solid-state NMR Group, Department of NMR Based Structural Biology, Max-Planck-Institute for Biophysical Chemistry, Goettingen, Germany.
Awards and Fellowships
- Ramalingaswami Fellowship from Department of Biotechnology, Govt. of India. 2011-2015.
- Marie-Curie Fellowship from European Union under IIF FP7 framework for Post-doctoral Fellowship during 2008-2010.
- Alexander-von-Humboldt Fellowship for Post-doctoral research. (did not avail).
- Max-Planck-Fellowship for Post-doctoral research during 2007-2008.
Publications
- Joshi S, Khatri L K, Kumar A, Rathore S A. Monitoring size and oligomeric-state distribution of therapeutic mAbs by NMR and DLS: Trastuzumab as a case study J Pharm Biomed Anal.2021
- Sarkar S, Purusottom N R, Kumar A, Khaneja N. Chirp pulse sequences for broadband π rotation J Magn Reson. 2021
- Pravin N, Kumar R, Tripathi S, Kumar P, Mohite GM, Navalkar A, Panigrahi R, Singh N, Gadhe LG, Manchanda S, Shimozawa M, Nilsson P, Johansson J, Kumar A, Maji SK, Shanmugam M. Benzimidazole‐based Fluorophores for the Detection of Amyloid Fibrils with Higher Sensitivity than Thioflavin‐T J. Neurochem. 2021
- Sharma, K.; Mehra, S.; Sawner, A. S.; Markam, P. S.; Panigrahi, R.; Navalkar, A.; Chatterjee, D.; Kumar, R.; Kadu, P.; Patel, K. Effect of Disease-Associated P123H and V70M Mutations on β-Synuclein Fibrillation ACS Chem. Neurosci. 2020.
- Bishoyi, A. K.; Roham, P. H.; Rachineni, K.; Save, S.; Hazari, M. A.; Sharma, S.; Kumar, A. Human Islet Amyloid Polypeptide (HIAPP)–a Curse in Type II Diabetes Mellitus: Insights from Structure and Toxicity Studies Biol. Chem. 2020
- Ray, S.; Singh, N.; Kumar, R.; Patel, K.; Pandey, S.; Datta, D.; Mahato, J.; Panigrahi, R.; Navalkar, A.; Mehra, S. α-Synuclein Aggregation Nucleates through Liquid–Liquid Phase Separation Nat. Chem. 2020
- Dubey R, Kulkarni SH, Dantu SC, Panigrahi R, Sardesai DM, Malik N, Acharya JD, Chugh J, Sharma S, Kumar A. Myricetin protects pancreatic β-cells from human islet amyloid polypeptide (hIAPP) induced cytotoxicity and restores islet function Biol Chem. 2020
- Bhattacharya, A.; Shukla, V. K.; Hosur, R. V; Kumar, A. Backbone and Side-Chain Resonance Assignments of Centromeric Protein Scm3 from Saccharomyces Cerevisiae Biomol. NMR Assign.2019
- Dubey, R.; Patil, K.; Dantu, S. C.; Sardesai, D. M.; Bhatia, P.; Malik, N.; Acharya, J. D.; Sarkar, S.; Ghosh, S.; Chakrabarti, R. Azadirachtin Inhibits Amyloid Formation, Disaggregates Pre-Formed Fibrils and Protects Pancreatic β-Cells from Human Islet Amyloid Polypeptide/Amylin-Induced Cytotoxicity Biochem. J.2019
- Vasudevan, S. V; Kumar, A. Antimicrobial Peptide ROAD–1 Triggers Phase Change in Local Membrane Environment to Execute Its Activity J. Mol. Model.2019