Kunwar, Ambarish

Dr. Ambarish Kunwar

Associate Professor

Phone: +(91-22) 2576 7799
Fax: +(91-22) 2572 7760
E-mail: akunwar [at] iitb(dot)ac(dot)in
Location: Lab No. 204, BSBE Building
Lab web page Link

Research Interest
Our lab works in the area of biophysics and computational biology and uses Monte-Carlo Simulations and Molecular Dynamics simulations to understand

  • Transport and force generation by motor Proteins
  • Interaction of anti-cancer drugs with microtubules
  • Interaction of microtubule associated proteins (MAPs) with microtubules

Professional Experience

  • Associate Professor: Indian Institute of Technology Bombay, 2016
  • Assistant Professor : Indian Institute of Technology Bombay, 2012
  • Assistant Professor : Indian Institute of Technology Gandhinagar, 2011-2012
  • Postdoctoral Scholar : Department of Neurobiology, Physiology & Behavior, University of California Davis, 2008-2011
  • Postdoctoral Scholar : Department of Developmental and Cell Biology, University of California Irvine, 2006-2008

Academic Background

  • B.Sc. (Honours): Banaras Hindu University, 1999
  • M.Sc. (Physics): Banaras Hindu University, 2001
  • Ph.D.: Indian Institute of Technology Kanpur, 2006
Awards / Honors
  • Innovative Young Biotechnologist Award for the year 2012 (IYBA 2012), Department of Biotechnology, India
  • Young Faculty Award, IIT Bombay
  • Excellence-in-Research Fellowship, IIT Gandhinagar

Selected Recent Publications

  1. Vishwambhar Bhandare, Bajarang Vasant Kumbhar and Ambarish KunwarDifferential binding affinity of tau repeat region R2 with neuronal specific β-tubulin isotypes, Scientific Reports 9, 10795 (2019)
  2. Carlos M. Guardia, Raffaella De Pace, Aritra Sen, Amra Saric, Michal Jarnik, David A. Kolin, Ambarish Kunwar, Juan S. Bonifacino, Reversible association with motor proteins (RAMP): A streptavidin-based method to manipulate organelle positioning, PLoS Biology 17(5): e3000279 (2019)
  3. Bajarang Vasant Kumbhar, Vishwambhar Bhandare, Dulal Panda and Ambarish Kunwar, Delineating the Interaction of Combretastatin A-4 with αβ tubulin Isotypes present in Drug Resistant Human Lung Carcinoma using a Molecular Modeling Approach, Journal of Biomolecular Structure and Dynamics. DOI: 10.1080/07391102.2019.1577174 (2019)
  4. Bajarang Vasant Kumbhar, Dulal Panda and Ambarish Kunwar, Interaction of microtubule depolymerizing agent indanocine with different human αβ tubulin isotypes, PLoS ONE 13(3): e0194934 (2018)
  5. Anjneya Takshak, Tanushree Roy, Parag Tandaiya and Ambarish Kunwar, Effect of Fuel Concentration and Force on Collective Transport by a Team of Dynein Motors, Protein Science, Vol. 26, 186–197 (2017) 2015 Journal Impact Factor = 3.039
  6. Weili Hong, Anjneya Takshak, Olaolu Osunbayo, Ambarish Kunwar and Michael Vershinin, The Effect of Temperature on Microtubule-Based Transport by Cytoplasmic Dynein and Kinesin-1 Motors, Biophysical Journal, Vol. 111, 1287 (2016)
  7. Bajarang Vasant Kumbhar, Anubhaw Borogaon, Dulal Panda and Ambarish Kunwar, Exploring the Origin of Differential Binding Affinities of Human Tubulin Isotypes αβII, αβIII and αβIV for DAMA-colchicine using Homology Modelling, Molecular Docking and Molecular Dynamics Simulation, PLoS ONE 11(5): e0156048 (2016)
  8. Anjneya Takshak and Ambarish Kunwar, Importance of anisotropy in detachment rates for force production and cargo transport by a team of motor proteins, Protein Science, Vol. 25, 1075 (2016) 2015 Journal Impact Factor = 3.039