• Prototype of UVC based Robotic Disinfection System

Welcome to the Biophysics and BioInnovations Laboratory. Our lab is engaged in both basic science-oriented as technology development-oriented research. Summary of our ongoing lab projects is given below:

Basic Science-oriented Research Projects

Transport and force generation by a team of molecular motor proteins: Transport and force generation by motor proteins such as kinesin, dynein and myosin is important for cell growth and cell division. Impairment of transport and force generation by motor proteins is linked to various neurological diseases and cancer. We develop experimentally constrained computational (Monte-Carlo) models to understand transport and force generation by a team of motor proteins.

Interaction of potential anti-cancer drugs and MAPs with microtubules: These studies enable us to identify molecular reasons behind the development of drug resistance in cancerous cells, the interaction of microtubule-associated proteins (MAPs) with microtubules under normal and diseased conditions. We use a combination of computational approaches consisting of homology modeling, molecular docking, and molecular dynamics (MD) simulations. We also apply machine learning algorithms to these problems to get better understanding of biomolecular interactions.

Effect of pathogenic variation on proteins involved in Endocrine diseases: We have started to work very closely with clinicians at Department of Endocrinology at Seth G.S Medical College & KEM Hospital, Mumbai to understand the interaction of various proteins involved in endocrine diseases with hormones and drugs under normal and diseased conditions. We again use a combination of computational approaches consisting of homology modeling, molecular docking, and molecular dynamics simulations to understand the molecular reasons behind the disease.

Pathogen inactivation by Far-UVC: We have been studying efficacy of Far-UVC radiation for pathogen inactivation as far-UVC radiation is considered safer than conventional UVC radiation. We have recently established that far-UVC radiation inactivation both single and double stranded DNA and RNA viruses with better efficacy.

Technology Development-oriented Projects

Robotic and Non-robotic UVC based disinfection Devices: Since the beginning of the COVID-19 pandemic in India, we have started to work on developing various UV-based sterilization solutions. We developed three products- Portable UV Sanitizer, Germicidal UV cabinet and Wheeled sterilization unit for large areas. Product prototypes have been tested for inactivation and have been licensed to the industry. In addition, we have also taken up consultancy projects from industries to help them in developing/testing UV-based and ozone-based disinfection solutions.

Motion and Gait planning for robotic animals: Our lab is developing open-source design of quadrupeds and algorithms for their gait and motion planning. We also intend to use machine learning algorithms for gait and motion planning of these robotic animals.

Development of neurorobotic model: One of the lab project is to develop neurorobotic model of mice to find out role of different brain circuits which are involved tremors and gait impairment in case of neurological disorders and diseases.

IoT-based system for monitoring and controlling indoor air ventilation: My lab is also working on developing an IoT-based system for continuous monitoring and control of the indoor air ventilation and air quality.

Low-cost microscopes for education: Our lab has also developed prototypes of different types of low-cost microscopes for education that can be assembled within between Rs. 50 to Rs. 500.

Basic Science-oriented Projects

  • Transport and Force Generation by a Team of Motor Proteins

Technology Development-oriented Projects

  • Robotic UVC Sterization Unit-ArmBot


  • Online IITBombayX course "Technical Communication for Scientists and Engineers"


  • Innovative Young Biotechnologist Award (IYBA) for Year 2012

Educational Outreach Activities

  • Coordinator, QIP/CEP course “Biology for Engineers”, IIT Bombay, June 06-11, 2016


  • Organizer, International Symposium “Experimental and Computational Studies of Microtubules and Microtubule based Motor Proteins”