• Prototype of UVC based Robotic Disinfection System

Welcome to the Biophysics and BioInnovations Laboratory at the Department of Biosciences and Bioengineering of IIT Bombay. Our lab is engaged in both inter-disciplinary science-oriented as technology development-oriented research projects. Our lab works on biological problems using an inter-disciplinary approach to solve challenging scientific problems and developing technologies. A summary of our ongoing lab projects is given below:

Basic Science-oriented Research Projects

The aim of our inter-disciplinary research is to understand these biological systems/phenomena using physical and computational modeling. We mainly use Monte-Carlo modeling to develop computational models for biological systems/phenomena. We work with experimentalists very closely to develop, test, and further refine the models. This helps us to understand and help interpret experimental results as well as guiding further experiments by making experimentally testable predictions.

Transport and force generation by a team of molecular motor proteins: Transport and force generation by motor proteins such as kinesin, dynein and myosin is important for cell growth and cell division. Impairment of transport and force generation by motor proteins is linked to various neurological diseases and cancer. We develop experimentally constrained computational models to understand transport and force generation by a team of motor proteins.

Interaction of potential anti-cancer drugs and MAPs with microtubules: These studies enable us to identify molecular reasons behind the development of drug resistance in cancerous cells, the interaction of microtubule-associated proteins (MAPs) with microtubules under normal and diseased conditions. We use a combination of computational approaches consisting of homology modeling, molecular docking, and molecular dynamics simulations.

Effect of pathogenic variation on proteins involved in Endocrine diseases: We have started to work very closely with clinicians at Department of Endocrinology at Seth G.S Medical College & KEM Hospital, Mumbai to understand the interaction of various proteins involved in endocrine diseases with hormones and drugs under normal and diseased conditions. We again use a combination of computational approaches consisting of homology modeling, molecular docking, and molecular dynamics simulations to understand the molecular reasons behind the disease.

Technology Development-oriented Projects

Robotic and Non-robotic UVC based disinfection Devices: Since the beginning of the COVID-19 pandemic in India, we have started to work on developing various UV-based sterilization solutions. We developed three products- Portable UV Sanitizer, Germicidal UV cabinet and Wheeled sterilization unit for large areas. Product prototypes have been tested for inactivation and have been licensed to the industry. In addition, we have also taken up consultancy projects from industries to help them in developing/testing UV-based and ozone-based disinfection solutions. Very recently, we have developed two different types of UVC based robotic disinfection units. We have been working toward far-UVC based robotic units along with industry partners.

IoT-based system for monitoring and controlling indoor air ventilation: My lab is also working on developing an IoT-based system for continuous monitoring and control of the UVGI based air disinfection system is not available.

Low-cost microscopes for education: Our lab has also developed prototypes of different types of low-cost microscopes for education that can be assembled within between Rs. 50 to Rs. 500.

Motion and Gait planning for robotic animals: Our lab is developing open-source design of quadrupeds and algorithms for their gait and motion planning

Basic Science-oriented Projects

  • Transport and Force Generation by a Team of Motor Proteins

Technology Development-oriented Projects

  • Robotic UVC Sterization Unit-ArmBot


  • Online IITBombayX course "Technical Communication for Scientists and Engineers"


  • Innovative Young Biotechnologist Award (IYBA) for Year 2012

Educational Outreach Activities

  • Coordinator, QIP/CEP course “Biology for Engineers”, IIT Bombay, June 06-11, 2016


  • Organizer, International Symposium “Experimental and Computational Studies of Microtubules and Microtubule based Motor Proteins”