Phale, P.S.

Dr. Prashant S. Phale
Professor

Phone: +(91-22) 2576 7836
E-mail: pphale [at] iitb.ac.in
Location: Room No. 405, BSBE Building

Research Interest

  • Elucidation of metabolic pathways for degradation of aromatic compounds, Purification and characterization of oxygenases, Preferential utilization of aromatics compounds by Pseudomonas, Metabolic engineering of aromatic degradation pathways 

Academic Background

  • B.Sc. Ahemadnagar college, University of Poona, Poona (Microbiology)
  • M.Sc. Maharaja Sayajirao University, Baroda (Biotechnology)
  • Ph.D. Indian Institute of Science, Bangalore (Microbiology)

Teaching (current)

Analytical Biochemistry, Biochemistry Laboratory, Microbiology Laboratory

Professional Experience

  • Associate Professor: School of Biosciences & Bioengineering, IIT Bombay
  • Assistant Professor : School of Biosciences & Bioengineering, IIT Bombay
  • Post Doctoral Research Fellow: Harvard Medical School, Boston, USA
  • Post Doctoral Fellow: Biozentrum, University of Basel, Switzerland  

Memberships

  • Life member of:

    • National Academy of Sciences, India
    • Society of Biological Chemists, India
    • Association of Microbiologist of India
    • Biotechnology Research Society of India

Key Publications

  • Mohapatra B, Nain S, Sharma R, Phale PS. (2022). Functional genome mining and taxono-genomics reveal eco-physiological traits and species distinctiveness of aromatic-degrading Pseudomonas bharatica sp. nov. Environmental Microbiology Reports, 14: 464-474. DOI:10.1111/1758-2229.13066
  • Dhamale T, Saha BK, Papade SE, Singh S, Phale PS. (2022). A unique global metabolic trait of Pseudomonas bharatica CSV86T: metabolism of aromatics over simple carbon sources and co-metabolism with organic acids. Microbiology (United Kingdom), 168,
    DOI:10.1099/mic.0.001206
  • Mohapatra B, Malhotra H, Phale PS. (2022). Life Within a Contaminated Niche: Comparative Genomic Analyses of an Integrative Conjugative Element ICEnahCSV86 and Two Genomic Islands From Pseudomonas bharatica CSV86T Suggest Probable Role in Colonization and Adaptation. Frontiers in Microbiology, 13. DOI:10.3389/fmicb.2022.928848
  • Sharma A, Kalyani P, Trivedi VD, Kapley A, Phale PS. (2019). Nitrogen-dependent induction of atrazine degradation pathway in Pseudomonas sp. strain AKN5. FEMS Microbiology Letters, 366. DOI:10.1093/femsle/fny277
  • Kamini SR, Punekar NS, Phale PS. (2018) Carbaryl as a carbon and nitrogen source: An inducible methylamine metabolic pathway at the biochemical and molecular levels in Pseudomonas sp. strain C5pp. Applied and Environmental Microbiology, 84. DOI:10.1128/AEM.01866-18
  • Trivedi VD, Jangir PK, Sharma R, Phale PS. (2017) Erratum: Insights into functional and evolutionary analysis of carbaryl metabolic pathway from Pseudomonas sp. strain C5pp. Scientific reports, 7: 40899. DOI:10.1038/srep40899
  • Trivedi VD, Bharadwaj A, Varunjikar MS, Singha AK, Upadhyay P, Gautam K, Phale PS. (2017) Insights into metabolism and sodium chloride adaptability of carbaryl degrading halotolerant Pseudomonas sp. strain C7. Archives of Microbiology, 199: 907-916. DOI:10.1007/s00203-017-1363-4
  • Choudhary A, Purohit H, Phale PS. (2017) Benzoate transport in Pseudomonas putida CSV86. FEMS Microbiology Letters, Volume 364. DOI:10.1093/femsle/fnx118
  • Mohan K, Phale PS. (2017) Carbon source-dependent inducible metabolism of veratryl alcohol and ferulic acid in Pseudomonas putida CSV86. Applied and Environmental Microbiology, 83. DOI:10.1128/AEM.03326-16
  • Choudhary A, Modak A, Apte SK, Phale PS. (2017) Transcriptional modulation of transport- and metabolism-associated gene clusters leading to utilization of benzoate in preference to glucose in Pseudomonas putida CSV86. Applied and Environmental Microbiology, 83. DOI:10.1128/AEM.01280-17

The metabolic pathways contributed to ‘The University of Minnesota Biocatalysis/Biodegradation Database’

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