Quantitative views of modern biology. Importance of illustrations and building quantitative/qualitative models. Role of estimates. Cell size and shape. Temporal scales. Relative time in Biology. Key model systems – a glimpse. Management and transformation of energy in cells. Mathematical view – binding, gene expression and osmotic pressure as examples. Metabolism. Cell communication. Genetics. Eukaryotic genomes. Genetic basis of development. Evolution and diversity. Systems biology and illustrative examples of applications of Engineering in Biology.