Bhaumik, P

Dr. Prasenjit Bhaumik

Associate Professor

Phone: +(91-22) 2576 7748
Fax: +(91-22) 2572 7760
E-mail: pbhaumik [at] iitb.ac.in
Location: Room 603, BSBE Building
Lab web page

Research Interest

Understanding the structure function relationship of enzymes and biological macromolecules. Protein crystallography, Structure based antimalarial drug development, Structural enzymology

Academic Background

  • B.Sc. (Chemistry), 1997: University of Calcutta, Kolkata, India
  • M.Sc. (Biotechnology), 1999: Indian Institute of Technology-Bombay, Mumbai, India
  • Ph.D. (Biochemistry), 2006: University of Oulu, Oulu, Finland

Professional Experience

  • Postdoctoral Fellow (October 2006 – August 2011): National Cancer Institute at Frederick, NIH, USA
  • Assistant Professor: Department of Biosciences and Bioengineering, IIT Bombay

Awards

  • Poster prize winner, 40th Mid-Atlantic Protein Crystallography Meeting, USA, 2010
  • Fellows Award for Research Excellence (FARE) award from the NIH, 2009
  • Travel award from American Society of Biochemistry and Molecular Biology (ASBMB), 2009
  • Postdoctoral fellowship from National Cancer Institute, NIH, USA, 2006-2011
  • Ph.D. scholarship from Biocenter Oulu, University of Oulu, Finland, 2000-2006
  • Poster prize winner, Third Annual Conference of the Indian Environmental Association (IEA), 2000
  • National merit scholarship from DBT, Govt. of India, 1997-1999


Selected Publications

  • Bryksa, B. C., Bhaumik, P., Magracheva, E., De Moura, D. C., Kurylowicz M., Zdanov, A., Dutcher, J. R., Wlodawer, A. and Yada, R. Y. (2011) Structure and mechanism of the saposin-like domains of a plant aspartic protease. The Journal of Biological Chemistry 286:28265-28275.
  • Bhaumik, P., Gustchina, A. and Wlodawer, A. (2011) Structural studies of vacuolar plasmepsins. Biochimica et Biophysica Acta. doi:10.1016/j.bbapap.2011.04.008.
  • Bhaumik, P., Xiao, H., Parr, C., Kiso, Y., Gustchina, A., Yada, R. Y. and Wlodawer, A. (2009) Crystal structure of Histo-aspartic protease (HAP) from Plasmodium falciparum. Journal of Molecular Biology 388:520-540.
  • Bhaumik, P., Schmitz, W., Hassinen, A., Hiltunen, J. K., Conzelmann, E. and Wierenga, R. K. (2007) The catalysis of the 1,1-proton transfer by α-methyl-acyl-CoA racemase is coupled to a movement of the fatty acyl moiety over a hydrophobic, methionine-rich surface. Journal of Molecular Biology 367:1145-1161.
  • Bhaumik, P., Koski, M. K., Bergmann, U. and Wierenga, R. K. (2004) Structure determination and refinement at 2.44 Å resolution of argininosuccinate lyase from Escherichia coli. Acta Crystallographica Section D-Biological Crystallography 60:1964-1970.