Publications
Books:
D. Razansky, S. K. Kalva, V. Gujrati, V. Ntziachristos. “Optical and Optoacoustic Imaging.” In: Schober, O., Kiessling, F., Debus, J. (eds) Molecular Imaging in Oncology – Volume 1. Recent Results in Cancer Research, vol 224. Springer, Cham Springer, 2026.
[link]
S. K. Kalva and M. Pramanik. “Photoacoustic Tomography with High-Energy Pulsed Laser Diodes,” SPIE Press, 2020.
[link]
† Authors contributed equally · * Corresponding author
Journal publications: 2024 - present
[43]. R. Zhang†, X. L. Deán-Ben†, R. A. Barmin†, G. Mavrakis, E. Remlova, S. Banerjee, S. K. Kalva, S. Thoröe-Boveleth, D. N. Chigrin, E. M. Buhl, B. Becker, J. Köhler, F. Keissling, T. Lammers, R. Pallares*, D. Razansky*, “Whole-body Optoacoustic Tomography Unveils Shape-Directed Organ Targeting Dynamics of Gold Nanostars,” (2026). (in review)
[42]. J. Gröhl*, S. K. Kalva, B. Lafci, F. D. Cecio, R. Tao, T. R. Else, L. Wright, D. Razansky, and S. E. Bohndiek*, “OpenQPAIData: Measurements of test objects with reference labels for quantitative photoacoustic imaging research,” Scientific Data 13(1), 1127 (2026). [Link]
[41]. A. Ranjan, M. N. Jensen, A. Dubey, S. K. Kalva*, “Integrating Optoacoustic Microscopy with Existing and Emerging Imaging Modalities: A Review,” Biomedical Engineering Letters (2026). [link]
[40]. Y. Xu, X. Liu, X. L. Deán-Ben, S. K. Kalva*, D. Razansky*, “Efficient Denoising in LED-Based Optoacoustic Tomography with Squeeze-and-Excitation Deep Convolutional Networks,” Journal of Biomedical Optics 31(4), 046003 (2026). [link]
[39]. Y. Xu, X. Liu, X. Li, S. K. Kalva, J. Buhmann, D. Razansky, X. L. Deán-Ben*, “Diffusion-Based Model as a Generalizable Denoiser for Optoacoustic Imaging,” Computers in Biology and Medicine 200, 111340 (2026). [link]
[38]. S. K. Kalva†, C. Özsoy†, D. Nozdriukhin, S. Tiemann, L. Tang, X. L. Deán-Ben, D. Razansky*, “Toward noninvasive optoacoustic imaging of whole-heart dynamics in mice,” Light: Science & Applications 14(1), 391 (2025). [link]
[37]. S. K. Kalva†, X. Liu†, X. L. Deán-Ben, L. Tang, D. Razansky*, “LED-based optoacoustic tomography of mice,” Journal of Biomedical Optics 30(4), 040501 (2025). [link]
[36]. N. Mahkam, M. C. Ugurlu, S. K. Kalva, A. Aghakhani*, D. Razansky*, Metin Sitti*, “Multi-Orifice Acoustic Microrobot for Boundary-Free Multimodal 3D Swimming,” Proceedings of the National Academy of Sciences 122 (4), e2417111122, (2025). [link]
[35]. B. F. Combes†, S. K. Kalva†, P. L. Benveniste, A. Tournant, M. H. Law, J. Newton, M. Krüger, R. Z. Weber, I. Dias, D. Noain, X. L. Deán-Ben, U. Konietzko, C. R. Baumann, P. G. Gillberg, C. Hock, R. M. Nitsch, J. Cohen-Adad, D. Razansky*, R. Ni*, “Spiral volumetric optoacoustic tomography of reduced oxygen saturation in the spinal cord of M83 mouse model of Parkinson’s disease,” European Journal of Nuclear Medicine and Molecular Imaging 52 (2), 427-443, (2025). [link]
[34]. S. K. Kalva, A. Özbek, M. Reiss, X. L. Deán-Ben, D. Razansky*, “Spiral volumetric optoacoustic and ultrasound (SVOPUS) tomography of mice,” Photoacoustics 40, 100659 (2024). [link]
[33]. L. Tang†, D. Nozdriukhin†, S. K. Kalva, Q. Zhou, C. Özsoy, S. Lyu, M. Reiss, A. Vidal, A. Torres, X. L. Deán-Ben*, D. Razansky*, “Scalable copper sulfide formulations for super-resolution optoacoustic brain imaging in the second near-infrared window,” Small Methods, e2400927, (2024). [link]
Journal publications: 2016 – 2023
[32]. D. Nozdriukhin*, S. K. Kalva, C. Özsoy, M. Reiss, W. Li, D. Razanky, X. L. Deán-Ben, “Multi-scale Volumetric Dynamic Optoacoustic and Laser Ultrasound (OPLUS) Imaging Enabled by Semi-Transparent Optical Guidance,” Advanced Science, 2306087 (2023). [link] [IF:15.1]
[31]. E. A. Maksimova†, D. Nozdriukhin†, S. K. Kalva, S. Lyu, B. Lafci, M. A. Augath, P. G. Rudakovskaya, A. A. Solovev, Y. Mei, X. L. Deán-Ben*, D. Razansky*, D. A. Gorin*, “Multilayer Polymer Shell Perfluoropentane Nanodroplets for Multimodal Ultrasound, Magnetic Resonance, and Optoacoustic Imaging,” Laser & Photonics Reviews, 2300137 (2023). [link] [IF:10.947]
[30]. X. Liu†, S. K. Kalva†*, B. Lafci, D. Nozdriukhin, X. L. Deán-Ben, D. Razanky*, “Full-view LED-based optoacoustic tomography,” Photoacoustics 31, 100521 (2023). [link] [IF:9.656]
[29]. S. K. Kalva, X. L. Deán-Ben, M. Reiss, D. Razansky*, “Spiral volumetric optoacoustic tomography for imaging whole-body biodynamics in small animals,” Nature Protocols 18, 2124 – 2142 (2023). [link] [IF:17.021]
[28]. S. K. Kalva, X. L. Deán-Ben, M. Reiss, D. Razansky*, “Head-to-tail imaging of mice with spiral volumetric optoacoustic tomography,” Photoacoustics 30, 100480 (2023). [link] [IF:9.656]
[27]. C. Yang†, W. Zhang†, X. Pang, F. Xiao, S. K. Kalva, Y. Zhang, M. Pramanik, L. Tian, G. Liu, M. Wang*, “Polyester-tethered near-infrared fluorophores confined in colloidal nanoparticles,” Aggregate e261, (2022). [link]
[26]. P. Wrede, O. Degtyaruk, S. K. Kalva, X. L. Deán-Ben, U. Bozuyuk, A. Aghakhani, B. Akolpoglu, M. Sitti*, D. Razansky*, “Real-time 3D optoacoustic tracking of cell-sized magnetic microrobots circulating in the mouse brain vasculature,” Science Advances 8(19), (2022). [link] [IF:14.957]
[25]. S. K. Kalva, A. S. Iglesias, X. L. Deán-Ben, L. M. L. Marzan, and D. Razansky*, “Rapid Volumetric Optoacoustic Tracking of Nanoparticle Kinetics Across Murine Organs,” ACS Applied Materials & Interfaces 14(1), 172-178 (2022). [link] [IF:10.383]
[24]. D. Nozdriukhin, S. K. Kalva, W. Li, A. Yashchenok, D. Gorin, D. Razansky, X. L. Deán-Ben*, “Rapid Volumetric Optoacoustic Tracking of Individual Microparticles In Vivo Enabled by a NIR-Absorbing Gold–Carbon Shell,” ACS Applied Materials & Interfaces 13(41), 48423-48432 (2021). [link] [IF:10.383]
[23]. J. Prakash*, S. K. Kalva, M. Pramanik, and P. K. Yalavarthy, “Binary Photoacoustic Tomography for Improved Vasculature Imaging,” Journal of Biomedical Optics 26(8), 086004 (2021). [link] [IF:3.758]
[22]. S. K. Kalva, X. L. Deán-Ben, D. Razansky*, “Single-Sweep Volumetric Optoacoustic Tomography of Whole Mice,” Photonics Research 9(6), 899-908 (2021). [link] [IF:7.254]
[21]. A. Ron, S. K. Kalva, V. Periyasamy, X. L. Deán-Ben, D. Razansky*, “Flash Scanning Volumetric Optoacoustic Tomography for High Resolution Whole-Body Tracking of Nanoagent Kinetics and Biodistribution,” Laser & Photonics Reviews 15, 2000484 (2021). [link] [IF:10.947]
[20]. N. Awasthi, S. K. Kalva, M. Pramanik, and P. K. Yalavarthy*, “Dimensionality Reduced Plug and Play Priors for Improving Photoacoustic Tomographic Imaging with Limited Noisy Data,” Biomedical Optics Express 12(3), 1320-1338 (2021). [link] [IF:3.562]
[19]. P. K. Yalavarthy, S. K. Kalva, M. Pramanik, and J. Prakash*, “Non-Local Means Improves Total-Variation Constrained Photoacoustic Image Reconstruction,” Journal of Biophotonics 14(1), e202000191 (2021). [link] [IF:3.39]
[18]. N. A. Rejesh, S. K. Kalva, M. Pramanik, and M. Arigovindan*, “Photoacoustic Tomographic Image Reconstruction from Reduced Data Using Physically Inspired Regularization,” Journal of Instrumentation 15, P12028 (2020). [link] [IF:1.121]
[17]. N. Awasthi†, G. Jain†, S. K. Kalva, M. Pramanik, and P. K. Yalavarthy*, “Deep Neural Network Based Sinogram Super-Resolution and Bandwidth Enhancement for Limited-Data Photoacoustic Tomography,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control 67(12), 2660-2673 (2020). [link] [IF:3.267]
[16]. J. Prakash†, D. Sanny†, S. K. Kalva, M. Pramanik, and P. K. Yalavarthy*, “Fractional Regularization to Improve Photoacoustic Tomographic Image Reconstruction,” IEEE Transactions on Medical Imaging 38(8), 1935-1947 (2019). [link] [IF:11.037]
[15]. S. K. Kalva, P. K. Upputuri, P. Rajendran, R. A. Dienzo, and M. Pramanik*, “Pulsed Laser Diode Based Desktop Photoacoustic Tomography for Monitoring Wash-In and Wash-Out of Dye in Rat Cortical Vasculature,” Journal of Visualized Experiments 147, e59764 (2019). [link] [IF:1.424]
[14]. N. Awasthi, K. R. Prabhakar, S. K. Kalva, M. Pramanik, R. V. Babu, and P. K. Yalavarthy*, “PA-Fuse: Deep Supervised Approach for The Fusion of Photoacoustic Images with Distinct Reconstruction Characteristics,” Biomedical Optics Express 10(5), 2227-2243 (2019). [link] [IF:3.562]
[13]. S. K. Kalva, P. K. Upputuri, and M. Pramanik*, “High-Speed, Low-Cost, Pulsed-Laser-Diode-Based Second-Generation Desktop Photoacoustic Tomography System,” Optics Letters 44(1), 81-84 (2019). [link] [IF:3.560]
[12]. A. Sharma, S. K. Kalva, and M. Pramanik*, “A Comparative Study of Continuous Versus Stop-And-Go Scanning in Circular Scanning Photoacoustic Tomography,” IEEE Journal of Selected Topics in Quantum Electronics 25(1), 7100409 (2019). [link] [IF:4.653]
[11]. S. Gutta, M. Bhatt, S. K. Kalva, M. Pramanik, and P. K. Yalavarthy*, “Modeling Errors Compensation with Total Least Squares for Limited Data Photoacoustic Tomography,” IEEE Journal of Selected Topics in Quantum Electronics 25(1), 6800214 (2019). [link] [IF:4.653]
[10]. D. R. Sanny, J. Prakash, S. K. Kalva, M. Pramanik, and P. K. Yalavarthy*, “Spatially Variant Regularization Based on Model Resolution and Fidelity Embedding Characteristics Improves Photoacoustic Tomography,” Journal of Biomedical Optics 23(10), 100502 (2018). [link] [IF:3.758]
[9]. N. Awasthi, S. K. Kalva, M. Pramanik, and P. K. Yalavarthy*, “Image Guided Filtering for Improving Photoacoustic Tomographic Image Reconstruction,” Journal of Biomedical Optics 23(9), 091413 (2018). [link] [IF:3.758]
[8]. S. Gutta, S. K. Kalva, M. Pramanik, and P. K. Yalavarthy*, “Accelerated Image Reconstruction Using Extrapolated Tikhonov Filtering for Photoacoustic Tomography,” Medical Physics 45(8), 3749-3767 (2018). [link] [IF:4.506]
[7]. N. Awasthi, S. K. Kalva, M. Pramanik, and P. K. Yalavarthy*, “Vector Extrapolation Methods for Accelerating Iterative Reconstruction Methods in Limited-Data Photoacoustic Tomography,” Journal of Biomedical Optics 23(7), 071204 (2018). [link] [IF:3.758]
[6]. S. K. Kalva, Z. Z. Hui, and M. Pramanik*, “Calibrating Reconstruction Radius in a Multi Single-Element Ultrasound-Transducer-Based Photoacoustic Computed Tomography System,” Journal of the Optical Society of America A 35(5), 764-771 (2018). [link] [IF:2.104]
[5]. S. Gutta, V. S. Kadimesetty, S. K. Kalva, M. Pramanik, S. Ganapathy, and P. K. Yalavarthy*, “Deep Neural Network-Based Bandwidth Enhancement of Photoacoustic Data,” Journal of Biomedical Optics 22(11), 116001 (2017). [link] [IF:3.758]
[4]. P. K. Upputuri, V. Periyasamy, S. K. Kalva, and M. Pramanik*, “A High-Performance Compact Photoacoustic Tomography System for In Vivo Small-Animal Brain Imaging,” Journal of Visualized Experiments 124, e55811 (2017). [link] [IF:1.424]
[3]. Y. Gawale, N. Adarsh, S. K. Kalva, J. Joseph, M. Pramanik*, D. Ramaiah*, and N. Sekar*, “Carbazole Linked NIR Aza-BODIPY Dyes as Triplet Sensitizers and Photoacoustic Contrast Agents for Deep Tissue Imaging,” Chemistry – A European Journal 23(27), 6570-6578 (2017). [link] [IF:5.020]
[2]. S. K. Kalva, and M. Pramanik*, “Use of Acoustic Reflector to Make Compact Photoacoustic Tomography System,” Journal of Biomedical Optics 22(2), 026009 (2017). [link] [IF:3.758]
[1]. S. K. Kalva, and M. Pramanik*, “Experimental Validation of Tangential Resolution Improvement in Photoacoustic Tomography Using a Modified Delay-And-Sum Reconstruction Algorithm,” Journal of Biomedical Optics 21(8), 086011 (2016). [link] [IF:3.758]
Conference proceedings
[16]. S. K. Kalva†, C. Özsoy†, D. Nozdriukhin, S. Tiemann, L. Tang, X. L. Deán-Ben, D. Razansky*, “Capturing whole-heart in vivo dynamics in mice with volumetric optoacoustic tomography,” Optica Biophotonics Congress: Optical Tomography and Spectroscopy 2026, paper OM3D.4. [Link]
[15]. J. Gröhl, S. K. Kalva, B. Lafci, F. D. Cecio, D. Razansky, S. E. Bohndiek*, “Bridging the simulation gap in photoacoustic imaging by calibration with tissue-mimicking phantoms,” Proc. SPIE, PC1284218 (2024). [link]
[14]. X. Liu†, S. K. Kalva†*, B. Lafci, D. Nozdriukhin, X. L. Deán-Ben, M. Reiss, and D. Razansky*, “Full-view low-cost LED-based optoacoustic tomography,” Proc. SPIE 12842, 128420G (2024). [link]
[13]. S. K. Kalva, X. L. Deán-Ben, M. Reiss, and D. Razansky*, “Spiral Volumetric Optoacoustic Tomography (SVOT) of mice from head to tail,” Proc. SPIE 12379, 123790G (2023). [link]
[12]. P. Wrede, O. Degtyaruk, S. K. Kalva, X. L. Deán-Ben, U. Bozuyuk, A. Aghakhani, B. Akolpoglu, M. Sitti*, D. Razansky*, “Optoacoustic Tracking and Magnetic Manipulation of Cell-Sized Microrobots in Mice,” Optica Biophotonics Congress: Biomedical Optics 2022, paper TTu4B.6. [link]
[11]. S. K. Kalva, X. L. Deán-Ben, M. Reiss, and D. Razansky*, “Whole body imaging of mice in under 2 sec with single-sweep volumetric optoacoustic tomography (sSVOT),” Proc. SPIE 11960, 1196005 (2022). [link]
[10]. D. Nozdriukhin, S. K. Kalva, W. Li, J. Zhao, A. Yashchenok, D. Gorin, D. Razansky, and X. L. Deán-Ben*, “Optoacoustic visualization of individual core-shell microparticles in vivo,” Proc. of SPIE 11960, 1196016 (2022). [link]
[9]. S. K. Kalva, A. Ron, V. Periyasamy, M. Reiss, X. L. Deán-Ben, and D. Razansky*, “Whole-body visualization of nanoagent kinetics in mice with flash scanning volumetric optoacoustic tomography,” Proc. SPIE 11642, 116420A (2021). [link]
[8]. J. Prakash, D. R. Sanny, S. K. Kalva, M. Pramanik, P. K. Yalavarthy, “Fractional regularization improves photoacoustic image reconstruction,” Proc. SPIE 11642, 1164236 (2021). [link]
[7]. S. K. Kalva, P. K. Upputuri, R. A. Dienzo, M. Pramanik*, “Pulsed laser diode based photoacoustic tomography system using multiple acoustic reflector based single element ultrasound transducers,” Proc. SPIE 10878, 1087831 (2019). [link]
[6]. S. K. Kalva, Z. Z. Hui, and M. Pramanik*, “Multiple single-element transducer photoacoustic computed tomography system,” Proc. SPIE 10494, 104944D (2018). [link]
[5]. A. Sharma, S. K. Kalva, and M. Pramanik*, “Comparison of continuous and stop-and-go scanning techniques in photoacoustic tomography,” Proc. SPIE 10494, 104943L (2018). [link]
[4]. P. K. Upputuri, S. K. Kalva, M. Moothanchery, and M. Pramanik*, “Pulsed laser diode photoacoustic tomography (PLD-PAT) system for fast in vivo imaging of small animal brain,” Proc. SPIE 10064, 100645O (2017). [link]
[3]. S. K. Kalva, and M. Pramanik*, “Compact photoacoustic tomography system,” Proc. SPIE 10064, 100643X (2017). [link]
[2]. S. K. Kalva, and M. Pramanik*, “Modified delay-and-sum reconstruction algorithm to improve tangential resolution in photoacoustic tomography,” Proc. SPIE 10064, 100643W (2017). [link]
[1]. S. K. Kalva, V. P. Pandiyan, and R. John*, “White light diffraction phase microscopy,” IJRET, 2015. [link]
Conference presentations
[16]. S. K. Kalva, C. Özsoy, D. Nozdriukhin, S. Tiemann, L. Tang, X. L. Deán-Ben, D. Razansky, “Capturing whole-heart in vivo dynamics in mice with volumetric optoacoustic tomography,” Optica Biophotonics Congress, Fort Lauderdale, FL, USA, April 2026 (Oral).
[15]. S. K. Kalva, C. Özsoy, D. Nozdriukhin, S. Tiemann, L. Tang, X. L. Deán-Ben, D. Razansky, “Capturing whole-heart in vivo dynamics in mice with volumetric optoacoustic tomography,” EMIM, Ljubljana, Slovenia, March 2026 (Poster).
[14]. S. K. Kalva, Ali Özbek, M. Reiss, X. L. Deán-Ben, and D. Razansky, “Whole-body imaging of mice with dual-modal spiral volumetric optoacoustic and ultrasound (SVOPUS) tomography,” SPIE Photonics West, San Francisco, CA, USA, January 2025 (Poster).
[13]. S. K. Kalva, X. L. Deán-Ben, A. Ozbek, M. Reiss, and D. Razansky, “Spiral volumetric optoacoustic and ultrasound (SVOPUS) tomography of mice,” EMIM, Porto, Portugal, March 2024 (Oral).
[12]. X. Liu, S. K. Kalva, B. Lafci, D. Nozdriukhin, X. L. Deán-Ben, M. Reiss, and D. Razansky, “Full-view LED-based optoacoustic tomography of human finger joints,” EMIM, Porto, Portugal, March 2024 (Poster).
[11]. S. K. Kalva, X. L. Deán-Ben, M. Reiss, and D. Razansky, “Spiral volumetric optoacoustic tomography for head-to-tail panoramic imaging of mice,” EMIM, Salzburg, Austria, March 2023 (Oral).
[10]. S. K. Kalva, X. L. Deán-Ben, M. Reiss, and D. Razansky, “Spiral volumetric optoacoustic tomography (SVOT) of mice from head to tail,” SPIE Photonics West, San Francisco, CA, USA, January 2023 (Oral).
[9]. S. K. Kalva, X. L. Deán-Ben, M. Reiss, and D. Razansky, “Whole body imaging of mice in under 2 sec with single-sweep volumetric optoacoustic tomography (sSVOT),” SPIE Photonics West, San Francisco, CA, USA, January 2022 (Oral).
[8]. S. K. Kalva, X. L. Deán-Ben, M. Reiss, and D. Razansky, “Single-sweep volumetric optoacoustic tomography for whole body imaging of mice,” EMIM, Göttingen, Germany, August 2021 (Oral).
[7]. S. K. Kalva, A. Ron, V. Periyasamy, X. L. Deán-Ben, M. Reiss, and D. Razansky, “Whole-body visualization of nanoagent kinetics in mice with flash scanning volumetric optoacoustic tomography,” SPIE Photonics West, San Francisco, CA, USA, February 2021 (Oral).
[6]. S. K. Kalva, P. K. Upputuri, R. A. Dienzo, and M. Pramanik, “Pulsed laser diode based photoacoustic tomography system using multiple acoustic reflector based single element ultrasound transducers,” SPIE Photonics West, San Francisco, CA, USA, February 2019 (Poster).
[5]. S. K. Kalva, Z. Z. Hui, and M. Pramanik, “Multiple single-element transducer photoacoustic computed tomography system,” SPIE Photonics West, San Francisco, CA, USA, January 2018 (Poster).
[4]. A. Sharma, S. K. Kalva, and M. Pramanik, “Comparison of continuous and stop-and-go scanning techniques in photoacoustic tomography,” SPIE Photonics West, San Francisco, CA, USA, January 2018 (Poster).
[3]. S. K. Kalva, and M. Pramanik, “Modified delay-and-sum reconstruction algorithm to improve tangential resolution in photoacoustic tomography,” SPIE Photonics West, San Francisco, CA, USA, February 2017 (Poster).
[2]. S. K. Kalva, and M. Pramanik, “Compact photoacoustic tomography system,” SPIE Photonics West, San Francisco, CA, USA, February 2017 (Poster).
[1]. P. K. Upputuri, S. K. Kalva, M. Moothanchery, and M. Pramanik, “Pulsed laser diode photoacoustic tomography (PLD-PAT) system for fast in vivo imaging of small animal brain,” SPIE Photonics West, San Francisco, CA, USA, February 2017 (Poster).
Invited talks
[2]. July 7, 2026: Monash University, Melbourne, Australia – “Scalable Optoacoustic Tomography: From High-Speed Volumetric Imaging to Accessible Low-Cost Systems”
[1]. October 1, 2025: AIIMS Bhopal, India — “Optoacoustic Imaging: Listening to Light”