Book Chapters
George E., Sen S., "Biomaterials in cancer research: from basic understanding to applications", Chapter 5, (Pages: 86–102) Biomaterial Mechanics, Taylor & Francis. Link
Kumar, S., Sen, S. ''Cadherin-Based Cell-Cell Adhesions: Adhesion Structure, Signalling and Computational Modeling'', Chapter-8, Intercellular Communication in Cancer (1st Ed), 2015. ISBN 978-94-017-7380-5 (eBook). DOI 10.1007/978-94-017-7380-5. Link
2023
Saxena N., Chakraborty S., Dutta S., Bhardwaj G., Karnik N., Shetty O., Jadhav S., Zafar H., Sen S., "Stiffness-dependent MSC homing and their differentiation to CAFs: Implications in breast cancer invasion" Journal of Cell Science., 2023.
Dutta S., Sen S., "Preparation and Characterization of Collagen-Hyaluronic Acid (Col-HA) Matrices: In Vitro Mimics of Tumor Microenvironment" Proteases and Cancer., 2023.
Piplani N., Roy T., Saxena N., Sen S., "Bulky glycocalyx shields cancer cells from invasion-associated stresses" Translational Oncology., 2023.
Jahan I., Ganesan V., Sahu M., Nandave M., Sen S., "Adhesivity-tuned bioactive gelatin/gellan hybrid gels drive efficient wound healing " International Journal of Biological Macromolecules., 2023.
2022
Goyal N., Barai A., Sen S., Kondabagil K., "Amoebal Tubulin Cleavage Late during Infection Is a Characteristic Feature of Mimivirus but Not of Marseillevirus" Microbiology Spectrum., 2022. Link to the Paper
Rajwar A., Shetty SR., Vaswani P., Morya V., Barai A., Sen S., Sonawane M., Bhatia D., "Geometry of a DNA Nanostructure Influences Its Endocytosis: Cellular Study on 2D, 3D, and in Vivo Systems" ACS Nano., 2022. Link to the Paper.
Mukerjee A., Sen S., "Mapping cytoskeletal stress concentrations and nuclear stresses during confined cell migration" Indian Journal of Physics., 2022. Link to the Paper
Sthanam L.K ., Roy T., Patwardhan S., Shukla A., Sharma S., Shinde P V., Tulasiram Kale H., P.Chandra Shekar., Kondabagil K., Sen S., "MMP modulated differentiation of mouse embryonic stem cells on engineered cell derived matrices" Biomaterials., 2022. Link to the paper
2021
Barai A., Mukerjee A., Das A., Saxena N., Sen S., "α-actinin-4 drives invasiveness by regulating of myosin IIB expression and myosin IIA localization" Journal of Cell Science., 2021. Link to the Paper
Patwardhan S., Mahdik P., Shetty O., Sen S., "ECM stiffness-tuned exosomes drive breast cancer motility through thrombospondin-1" Biomaterials., 2021. Link to the Paper
George E., Jahan I., Barai A., Ganesan V., Sen S., "High ligand density drives extensive spreading and motility on soft GelMA gels." Biomedical Materials., 2021. PubMed | Link to the Paper
Jahan I., Pandya J., Munshi R., Sen S., "Glycocalyx disruption enhances motility, proliferation and collagen synthesis in diabetic fibroblasts." Biochim Biophys Acta Mol Cell Res., 2021. PubMed | Link to the Paper
Saxena N., Jadav S., Sen S., "Fabrication of a microfluidic device for studying the combinatorial effect of physical and chemical cues on cell migration." STAR Protocols, 2021. PubMed | Link to the Paper
Barai A.*, Das A.*, Sen S., "Measuring microenvironment-tuned nuclear stiffness of cancer cells with atomic force microscopy." STAR Protocols, 2021 (*: Contributed equally). PubMed | Link to the Paper
Asadullah*, Kumar S.*, Saxena N., Sarkar M., Barai A., Sen S., "Combined heterogeneity in cell size and deformability promotes cancer invasiveness." Journal of Cell Science, 2021 (*: Contributed equally). Link to the Paper
Mukherjee A., Gupta A., Sen S.,Yan W., Saigal A., Singh R.K. , "Palpation sensitivity of an embedded nodule using the finite element method." ASME Journal of Engineering and Science in Medical Diagnostics and Therapy, 2021. Link to the Paper
Mal A., Bukhari A.B., Singh R.K., Kapoor A., Barai A., Deshpande I., Wadasadawala T., Ray P., Sen S., De A., "EpCAM Mediated Cellular Plasticity Promotes Radiation Resistance and Metastasis in Breast Cancer." Frontiers in Cell and Developmental Biology, 2021. Link to the Paper
2020
Mukherjee A., Barai A., Singh R.K., Yan W., Sen S., "Nuclear Plasticity Increases Susceptibility to Damage During Confined Migration." PLOS Computational Biology, 2020. PubMed | Link to the Paper
Uttam B., Jahan I., Sen S., Rao C.P., Coumarin–Calix[4]arene Conjugate-Anchored SiO2 Nanoparticles as an Ultrasensor Material for Fe3+ to Work in Water, in Serum, and in Biological Cells, ACS Omega 2020. PubMed | Link to the Paper
Ghate K., Mutalik SP., Sthanam L.K., Sen S., Ghose A., Fmn2 regulates growth cone motility by mediating a molecular clutch to generate traction forces, Neuroscience, 2020. bioRxiv link here | Link to the paper
Dutta S., Kumar S., Singh H., Khan M.A., Barai A, Tewari A., Rana R.S, Bera S., Sen S, Sahni A, Chemical evidence of preserved collagen in 54‐million‐year‐old fish vertebrae, Palaeontology, 2020. Link to the Paper
2019
Jahan I., George E., Saxena N., Sen S., Silver nanoparticle entrapped soft GelMA gels as prospective scaffolds for wound healing, ACS Applied Bio Materials, 2019. Link to the Paper
Das A., Barai A., Monteiro M., Kumar S., Sen S., Nuclear softening is essential for protease-independent migration, Matrix Biology, 2019. Link to the Paper
2018
Sthanam L.K., Saxena N., Mistari V., Roy T., Jadhav S., Sen S., Initial priming on soft substrates enhances subsequent topography-induced neuronal differentiation in ESCs but not in MSCs, ACS Biomaterials Science & Engineering, 2018. Link to the Paper
Mishra V., Rathore I., Arekar A., Sthanam L.K., Xiao H., Kiso Y., Sen S., Patankar S., Gustchina A., Hidaka K., Wlodawer A., Yada R.Y., Bhaumik P., Deciphering the mechanism of potent peptidomimetic inhibitors targeting plasmepsins – biochemical and structural insights, FEBS Journal, 2018. Link to the Paper
Kumar, S., Das, A., Sen, S., Multi-compartment cell-based modeling of confined migration: regulation by cell intrinsic and extrinsic factors, Mol. Biol. Cell, 2018. PubMed | Link to the Paper
George E., Barai A., Shirke P., Majumder A., Sen S., "Engineering Interfacial Migration by Collective Tuning of Adhesion Anisotropy and Stiffness", Acta Biomaterialia, 2018. Link to the Paper
Saxena N., Mogha P., Dash S., Majumder A., Jadhav S.*, Sen S*., "Matrix elasticity regulates mesenchymal stem cell chemotaxis", J. Cell Sci. 2018. (*: co-corresponding authors). Link to the Paper
Kumar S*., Das A.*, Barai A., Sen S., "MMP secretion rate and inter-invadopodia spacing collectively govern cancer invasiveness", Biophysical Journal, February 2018. (*: Contributed equally). Link to the Paper
Kapoor A.*, Barai A.*, Thakur B., Das A., Patwardhan S. R., Monteiro M., Gaikwad S., Bukhari A., Mogha P., Majumder A., De A., Ray P.#, Sen S.#, "Soft drug-resistant ovarian cancer cells migrate via two distinct mechanisms utilizing myosin II-based contractility", BBA Molecular Cell Research, February 2018. (*: contributed equally. #: co-corresponding authors). Link to the Paper
Desai S.*, Barai A.*, Bukhari A., De A.#, Sen S.#, "α-Actinin-4 confers radioresistance coupled invasiveness in breast cancer cells through AKT pathway", BBA Molecular Cell Research, January 2018 (*: contributed equally. #: co-corresponding authors). Link to the Paper
2017
Das A., Monteiro M., Barai A., Kumar S., Sen S., "MMP proteolytic activity regulates cancer invasiveness by modulating integrins", Scientific Reports, 2017. Link to the Paper.
This article has been selected as one of the top 100 read cell biology papers for Scientific Reports in 2017
Srinivasan S.*, Ashok V.*, Mohanty S., Das A., Das S., Kumar S., Sen S.#, Purwar R.#, "Blockade of Rho-associated protein kinase (ROCK) inhibits the contractility and invasion potential of cancer stem like cells", Oncotarget, 2017 (*: contributed equally. #: co-corresponding authors). Link to the Paper
Sthanam L. K., Barai A., Rastogi A., Mistari V. K., Maria A., Kauthale R., Gatne M. , Sen S., "Biophysical regulation of mouse embryonic stem cell fate and genomic integrity by feeder derived matrices", Biomaterials, 2017. Link to paper
Dey S. K., Singh R. K., Chattoraj S., Saha S., Das A., Bhattacharyya K., Sengupta K., Sen S., Jana S. S., "Differential role of nonmuscle myosin II isoforms during blebbing of MCF-7 cells.", Mol. Biol. Cell., 2017. PubMed Link
2016
Jacob R. S., Sen S., Maji S. K., "Adhesion of Human Mesenchymal Stem Cells and Differentiation of SH-SY5Y Cells on Amyloid Fibrils", Macromol. Symp, 2016. PDF
Surve, M. V., Anil A., Kamath K. G., Bhutda S., Sthanam L. K., Pradhan A., Srivastava R., Basu B., Dutta S., Sen S., Modi D., Banerjee A., "Membrane Vesicles of Group B Streptococcus Disrupt Feto-Maternal Barrier Leading to Preterm Birth", PLOS Pathogens, 2016. PDF
Kumar S., Kulkarni R., Sen S., "Cell motility and ECM proteolysis regulate tumor growth and tumor relapse by altering the fraction of cancer stem cells and their spatial scattering", Physical Biology, 2016. Link to paper
Reeba S. J.*, George E*, Singh P. K., Salot S., Anoop A., Jha N. N., Sen S.# and Maji S. K.#, "Cell adhesion on amyloid fibrils lacking integrin recognition motif", Journal of Biological Chemistry, 2016 (*: contributed equally. #: co-corresponding authors). PDF
Kumar S., Kapoor A., Desai S., Inamdar M. M.#, Sen S.#, “Proteolytic and non-proteolytic regulation of collective cell invasion: tuning by ECM density and organization.” Scientific Reports, 2016 (#: co-corresponding authors). PDF
2015
Soumya S. S., Gupta A., Cugno A., Deseri L., Dayal K., Das D., Sen S., Inamdar M. M., “Coherent motion of monolayer sheets under confinement and its pathological implications.” PloS Computational Biology, 2015.PDF
Das P., Saha P., Chandra S., Das A., Dey S. K., Das M. R., Sen S., Sarkar D. P., Jana S. S. “Phosphorylation of nonmuscle myosin II-A regulatory light chain resists Sendai virus fusion with host cells.” Scientific Reports , 2015. PDF
Jacob R. S., Ghosh D., Singh P. K., Basu S. K., Jha N. N., Das S., Sukul P. K., Patil S., Sathaye S., Kumar A., Chowdhury A., Malik S., Sen S., Maji S. K. “Self healing hydrogels composed of amyloid nano fibrils for cell culture and stem cell differentiation.” Biomaterials , 2015. PDF
Ghosh D., Singh P. K., Sahay S., Jha N. N., Jacob R. S., Sen S., Kumar A., Riek R., Maji S. K. “Structure based aggregation studies reveal the presence of helix-rich intermediate during a-Synuclein aggregation.” Scientific Reports , 2015. PDF
2014
Hansda D. K., Sen S.#, Padinhateeri R#, “Branching influences force-velocity curves and length fluctuations in actin networks.” Phys. Rev. E, 2014 (#: co-corresponding authors). PDF
Soumya S. S., Sthanam L. K., Padinhateeri R.#, Inamdar M. M.#, Sen S.#, “Probing Cellular Mechanoadaptation Using Cell-Substrate De-Adhesion Dynamics: Experiments and Model.” PloS ONE, 2014 (#:co-corresponding authors). PDF
Soumya S. S., Subodh K., George E., Basu S. K., Sen S.#, Inamdar M. M.#, “Spatial anisotropy and heterogeneity in contractility and adhesion distribution may contribute to cell steering during migration.” Applied Physics Letters, 2014 (#: co-corresponding authors). PDF
Kumar S., Das A., Sen S.,”Extracellular matrix density promotes EMT by weakening cell-cell adhesions.” Molecular BioSystems, 2014,10 (4),838 – 850. doi:10.1039/C3MB70431A. PDF
2013
Vichare S., Sen S.#, Inamdar M. M.#,”Cellular mechanoadaptation to substrate mechanical properties: contributions of substrate stiffness and thickness to cell stiffness measurements using AFM.” Soft Matter, 2013. doi:10.1039/C3SM51786A. (#: co-corresponding authors). PDF
Das A., Kapoor A., Mehta G. D., Ghosh S. K. and Sen S. “Extracellular matrix density regulates extracellular proteolysis via modulation of cellular contractility.” J Carcinogene Mutagene , 2013, S13:003, doi: 10.4172/2157-2518.S13-003. PDF
2012
Kapoor A, Sen S. “Synergistic modulation of cellular contractility by mixed extracellular matrices.” Int. J. Cell Biol., 2012, Article ID: 471591. PDF
Vichare S, Inamdar MM#, Sen S#. “Influence of cell spreading and contractility on stiffness measurements using AFM.” Soft Matter, 2012, 8, 10464-10471. (#: co-corresponding authors). PDF
2011
Mankar S, Anoop A, Sen S, Maji SK. “Nanomaterials: amyloids reflect their brighter side.” Nano Rev., 2011; 2. pii: 10.3402/nano.v2i0.6032. PDF
During postdoctoral research (U. C. Berkeley)
Sen S, Ng WP, Kumar S.”Contributions of talin-1 to glioma cell-matrix tensional homeostasis.” J R Soc Interface. , 2012, Jun 7;9(71):1311-7. PDF
Sen S, Ng WP, Kumar S. “Contractility Dominates Adhesive Ligand Density in Regulating Cellular De-adhesion and Retraction Kinetics.” Ann Biomed Eng. 2011 Apr;39(4):1163-73. Epub 2010 Oct 29. PDF
Lee J, Chu BH, Sen S, Gupte A, Chancellor TJ, Chang C, Ren F, Kumar S, Lele TP. “Modulating malignant epithelial tumor cell adhesion, migration and mechanics with nanorod surfaces.” Biomedical Microdevices, 2011 Feb;13(1):89-95. PDF
Lam WA, Cao L, Umesh V, Keung A, Sen S, Kumar S. “Extracellular matrix rigidity modulates neuroblastoma cell differentiation and N-myc expression.” Molecular Cancer, 2010. 9: 35. PDF
Sen S, Kumar S. “Combining mechanical and optical approaches to dissect cellular mechanobiology.” J Biomech, 2010. 43, 45-54. PDF
Sen S, Dong M, Kumar S. “Isoform-specific contributions of a-actinin to glioma cell mechanobiology.” PLoS ONE, 2009. 4(12), e8427. PDF
D’Sa DJ, de Juan Pardo EM, Rivas Astiz R. de las, Sen S, and Kumar S. “High-throughput indentational elasticity measurements of hydrogel extracellular matrix substrates,” Applied Physics Letters, 2009. 95, 063701. PDF
Sen S, Kumar S. “Cell-matrix de-adhesion dynamics reflect contractile mechanics,” Cellular and Molecular Bioengineering, 2009. 2(2): 218-230. PDF
During graduate research (Univ. of Pennsylvania)
Sen S*, Tewari M*, Zajac A, Barton E, Sweeney HL, Discher DE. “Upregulation of paxillin and focal adhesion signaling follows Dystroglycan Complex deletions and promotes a hypertensive state of differentiation,” Eur. J. Cell Biology, 2011 Feb-Mar;90(2-3):249-60. PDF
Sen S, Engler AJ, Discher DE. “Matrix strains induced by cells: Computing how far cells can feel,” Cellular and Molecular Bioengineering, 2009. 2(1): 39-48. PDF
Kim Y, Tewari M, Pajerowski JD, Cai S, Sen S, Williams J, Sirsi S, Lutz G, Discher DE. “Polymersome delivery of siRNA and antisense oligonucleotides,” J Controlled Release, 2009. 134(2): 132-40. PDF
Engler AJ, Rehfeldt F, Sen S, Discher DE. “Microtissue elasticity: measurements by Atomic Force Microscopy and its Influence on Cell Differentiation,” Methods Cell Biol., 2007. 83:521-45. PDF
Engler AJ, Sen S, Sweeney HL, Discher DE. “Matrix Elasticity Directs Stem Cell Lineage Specification,” Cell, 2006. 126(4): 677-698. PDF
Subramanian S, Parthasarathy R, Sen S, Boder ET, Discher DE. “Species and cell type-specific interactions between CD47 and human SIRP,” Blood, 2006. 107: 2548-2556. PDF
Subramanium S., Tsair R, Sen S, Dahl KN, Discher DE. “Membrane mobility and clustering of Integrin Associated protein (IAP, CD47)- Major differences between mouse and man and implications for signaling,” Blood Cells, Molecules and Diseases, 2006. 36(3): 364-372. PDF
Sen S, Subramanian S, Discher DE. “Indentation and adhesive probing of a cell membrane with AFM: theoretical model and experiments,” Biophysical J., 2005. 89(5): 3203-3213. PDF
Griffin MA, Sen S, Sweeney HL, Discher DE. “Adhesion-contractile balance in myocyte differentiation,” J. Cell Science, 2005. 117: 5855-5863. PDF
Engler AJ, Griffin MA, Sen S, Bonnemann CG, Sweeney HL, Discher DE. “Myotubes differentiate optimally on substrates with tissue-like stiffness: pathological implications for soft or stiff microenvironments,” J. Cell Biology, 2004. 166(6): 877-887. PDF
During Masters research (IIT Kanpur)
Sen S, Dasgupta B, Mallik AK. “Variational approach for singularity-free path-planning of parallel manipulators,” Mechanism and Machine Theory, 2003. 38(11): 1165-1183. PDF