Cellular Biophysics Lab
About our Lab
It is increasingly understood that the physical properties of the extracellular matrix (ECM) have a profound influence on cell behavior. These include the geometry, topography, and stiffness of the ECM. This has led to the growth of the new and exciting field of mechanobiology, where the goal is to study the influence of mechanics on various biological processes.
Our aim is to explore how development and cancer progression are regulated by the physical crosstalk between the cell cytoskeleton and the ECM. To contribute to this understanding we combine cell and molecular biology techniques with biophysical tools and computational approaches.
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UPDATES
Congratulation to Neha on her publication "Stiffness-dependent MSC homing and their differentiation to CAFs: Implications in breast cancer invasion" in Journal of Cell Science, 2023.
Congratulation to Niyati on her publication "Bulky glycocalyx shields cancer cells from invasion-associated stresses" in Translational Oncology, 2023.
Congratulation to Iffat on her publication "Adhesivity-tuned bioactive gelatin/gellan hybrid gels drive efficient wound healing " in International Journal of Biological Macromolecules, 2023.