Cellular Biophysics Lab
About our Lab
It is increasingly understood that the physical properties of the extracellular matrix (ECM) have a profound influence on cell behavior. These include the geometry, topography, and stiffness of the ECM. This has led to the growth of the new and exciting field of mechanobiology, where the goal is to study the influence of mechanics on various biological processes.
Our aim is to explore how development and cancer progression are regulated by the physical crosstalk between the cell cytoskeleton and the ECM. To contribute to this understanding we combine cell and molecular biology techniques with biophysical tools and computational approaches.
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UPDATES
Congratulations to Asad on his publication "MMP9 shapes cell mechanics to enable collective invasion in cancer" in npj systems biology and applications, 2025.
Congratulations to Tanusri on her publication "Nuclear compression-mediated DNA damage drives ATR-dependent Lamin expression and mouse ESC differentiation" in NAR, 2025.