IIT Bombay

Indian Institute of Technology (IIT) Bombay is known to be one of the premier institutes for the higher education and research in India. Over the years IIT Bombay has extended its abilities to contribute to quality teaching and research in almost all fields of science and technology through state-of-the-art facilities for academia and researchers. The Department of Biosciences and Bioengineering at IIT Bombay has put in balanced endeavors to be a part of basic science and applications in the field of biology, biomedical and bioengineering research.

Proteomics is an emerging field of research globally and IIT Bombay aims to keep-up the pace in this burgeoning field, which aims to identify proteins that are characteristic for disease formation & progression, and can potentially uncover diagnostic, prognostic markers or novel drug targets, and could help to understand the underlying mechanisms. IIT Bombay is emerging as a vibrant hub of bio-research and proteomics in India. At IIT Bombay currently research on proteomics and protein biochemistry is being pursued at various levels, e.g. Disease proteomics of glioblastoma, meningioma, malaria pathobiology, proteomics involving cell division of prokaryotic & eukaryotic cells, and recombinant proteins and protein structure analysis by developing and applying high end bioinformatics and statistical techniques.

To ensure high quality research, IIT has set its benchmark on par with some of the best institutes nationally and internationally. During the last two years IIT Bombay has set-up several high throughput platforms for the proteomics analysis such as GenePix4000B Microarray Scanner for Protein Microarray studies, OmniGrid Accent Microarrayer for printing of microarray slides, Autoflex MALDI TOF/TOF for mass spectrometry, 6550 iFunnel Q-TOF for mass spectrometry, Biacore T-200 for label free and protein interaction studies, Typhoon FLA 9500 scanner for 2D-DIGE experiments, Ettan IPGphor 3 IEF System and Ettan DALTsix electrophoresis units for 2D gel based experiments. Other facilities like High Performance Liquid Chromatography (HPLC), Fast Performance Liquid Chromatography (FPLC) and Protein sequencer are also available. For analyzing the sizable data generated through these high throughput techniques, IIT Bombay also boasts a list of sophisticated software dedicated to each of the above techniques such as Spectrum Mill, Mass Profiler Professional, Acuity, De cyder 2D Differential Analysis software, ImageMaster Platinum, BIAevaluation and Mascot are few amongst them.

Faculty expertise in the Department of Biosciences and Bioengineering, IIT Bombay ranges from the basic Biological Sciences to Biochemical Engineering and Computer Sciences and Engineering. This breadth and depth is necessary to meet the demands of Systems Biology and Omics research. Researchers at IIT Bombay look forward to contribute actively to the field of science with few groups dedicated to proteomics and systems biology research. Together, with the Proteomics Society, India, we share the vision to be innovative and pioneer, and contribute to cutting edge proteomics research to set benchmarks at the international level by interactions, collaborations and continued perseverance.

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