The Human Infectious Diseases HPP initiative (HID-HPP) is a world-wide coordinated enterprise toencourage and promote collaboration between scientists working on proteomics studies related to infectious diseases caused by virus, bacteria, fungi and parasites.
These infectious diseases are a leading cause of illness and death throughout the world, in particular in low income countries. Lower respiratory infections, HIV/AIDS and diarrheal diseases are ranked in the top ten causes of death globally, whereas malaria and tuberculosis are two of the major ten causes of death in low income countries. In developed countries infectious diseases are also important in immunosuppressed patients and transplant recipients. New diagnostic tests, therapeutic agents and vaccines are required to control these infectious diseases. International collaboration of scientists working in infectious diseases and proteomics is therefore essential to promote these researches.


The HID-HPP initiative was first devised during the 13th HUPO world congress held in Madrid 2014 and eventually settled during the Vancouver 2015 HUPO congress where the following topics were discussed:

  • How can the scientists working in proteomics of infectious diseases collaborate?
  • Development of SRM methods for detection and quantification of human and microbial proteins
  • Detection and quantification of these proteins by affinity or antibodies based technologies
  • Building of a web site to freely access data
  • Dissemination of HID-HPP activities (reports, special issues, etc.)
  • Organization and future actions
  • Characterization of microbial-host protein interaction networks
  • Identification of host factors as antimicrobial therapeutic targets